GeneChip® Targeted Genotyping Algorithm Enhancements for Release 1.5
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چکیده
With the launch of the GeneChip® Targeted Genotyping System 1.5, algorithm enhancements have been made to the Molecular Inversion Probe (MIP) data analysis algorithms. These improvements do not affect the overall framework of MIP data analysis described in [1]. Their effect on the data is to improve the quality of genotyping as well as the speed of clustering. Improvements vary according to the assay panel and experiments analyzed. We have tested the new algorithm on a wide variety of assay panels and found increases of 0-0.2% in trio accuracy, 0-0.3% in completeness and 0.31% in conversion (passed assays).
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